The adverse drug reactions to tumor necrosis factor alpha inhibitor

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منابع مشابه

The adverse drug reactions to tumor necrosis factor alpha inhibitor

Results In total, 111 subjects were enrolled. Mean age was 39.8¡3⁄411.7 years, and male was 68.5%. The diagnoses of subjects were AS (62.2%), RA (24%), CD (17%), and pyoderma gangrenosum (0.9%). The injected agents were adalimumab (53.2%), etanercept (29%), and infliximab (20.7%). Adverse drug reactions of 30.6% were reported. The most common adverse reactions were cutaneous reactions; 10 (9.0%...

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A human inhibitor of tumor necrosis factor alpha

Urine of some febrile patients exhibits a TNF-alpha inhibitory activity (TNF-alpha INH), sensitive to heat and trypsin, with an apparent mol wt of 40-60 X 10(3) and a pI range of 5.5-6.1. As for the Il-1 INH, the TNF INH activity involves a competitive mechanism of action suggesting the existence of a family of negative feedback-regulating molecules interfering with cytokines actions.

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Tumor Necrosis Factor Alpha Inhibitor-Induced Acute Pancreatitis

Treatment of acute pancreatitis remains a challenge, with therapy focused on supportive care and treating the inciting etiology. Tumor necrosis factor-alpha (TNFα) inhibitors have shown promising results treating acute pancreatitis in animal models, but they have not been evaluated in human trials yet. A 25-year-old woman presented with ulcerative colitis. She was unresponsive to immunomodulato...

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Sarcoidosis is a chronic multisystem disease of unknown etiology, characterized by noncaseating granulomatous infiltration of virtually any organ system. Treatment is often undertaken in an attempt to resolve symptoms or prevent progression to organ failure. Previous studies have suggested a prominent role for tumor necrosis factor-alpha (TNF-alpha) in the inflammatory process seen in sarcoidos...

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ژورنال

عنوان ژورنال: Clinical and Translational Allergy

سال: 2014

ISSN: 2045-7022,2045-7022

DOI: 10.1186/2045-7022-4-s3-p53